The upcoming El Niño event, a natural climate phenomenon, poses significant health risks globally, including extreme heat, drought, flooding, wildfires, and severe storms. These events can lead to heat-related illnesses, waterborne and vector-borne diseases, malnutrition, mental health issues, and disruptions to essential health services. As climate-related health risks escalate, preparedness and proactive measures are crucial. This webinar, organized by the WHO's EPI-WIN program, aims to address these challenges by gathering experts and partners to discuss global health risks associated with El Niño, share practical experiences, and explore strategies to enhance resilience and mitigate health impacts. The event will highlight priority health risks, such as heat-related illnesses and waterborne diseases, and emphasize the importance of strengthening emergency preparedness and anticipatory action. It will also promote collaboration across sectors to reduce health risks. By bringing together diverse stakeholders, the webinar will provide valuable insights and practical examples, enabling governments, health systems, and communities to better prepare for and respond to the health impacts of El Niño. This proactive approach is essential to safeguarding public health and building resilience in the face of climate-related challenges.